Jarrow Formulas Sam-e 200mg, 60 Tablets

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Jarrow Formulas SAM-e 200, 200mg, 60 TabletsAt a Glance:Contributes to the proper functioning of many biochemical systemsIdeal for those wanting to optimize cognitive function, mood, energy levels, liver activity and joint health*Preserved bioavailability through low-temp and low-moisture manufacturingProcessed without solventsProtected from degradation via enteric coating and blister-packaging

SAM-e contributes to the proper functioning of many biochemical systems.

S-adenosyl-L-methionine (SAM-e) is an amino acid derivative clinically documented to benefit brain, liver and joint function*. View larger.

The Multi-Functional Supernutrient

S-adenosyl-L-methionine (SAM-e) is an amino acid derivative clinically documented to benefit brain, liver and joint function.* Found in all living cells, SAM-e is called "activated methionine" and is formed via combination of ATP with methionine. Somewhat counterintuitively, however, methionine supplementation does not elevate SAM-e levels in the body. Rather, it elevates problematic homocysteine.

SAM-e has undergone many clinical trials involving thousands of human subjects. Researchers have identified many structure- and function-based benefits of SAM-e involving over 40 biochemical processes. It is a biochemical workhorse with various diverse effects on the body, including improving liver function, supporting joint health and lifting mood.*

Liver Detoxification

SAM-e metabolism supports glutathione (GSH) synthesis and glutathione-dependent enzymes, which support liver function.* GSH, the chief antioxidant and detoxifier inside cells, scavenges free radicals produced during carbohydrate breakdown for energy. Taurine is another end product of SAM-e metabolism. GSH and taurine are important for liver detoxification.*

Brain Function

SAM-e supports brain function by its methylation effects.* Methylation is the transfer of a methyl group (one carbon and three hydrogen atoms, CH3) from one molecule to another. SAM-e is the most important of all methyl-donors in mammalian metabolism. Donation of methyl groups supports numerous metabolic processes including brain function, energy production and DNA metabolism. Neurotransmitters, substances involved in nerve cell communication, are also products of methylation. These compounds include L-DOPA, dopamine, serotonin, epinephrine and phosphatidylcholine (in lecithin). SAM-e is thought to benefit cognitive health by supporting the production of such critical brain messengers.* In fact, many people report noticeable positive effects on brain and mood after only taking it for a short time.*

Energy Production

Methylation from SAM-e is also critical for creatine production. Creatine metabolites are important for ADP to ATP recycling and storing energy for immediate needs. Supporting creatine levels may help maximize physical performance, reduce exercise fatigue and improve recovery after exercise.*

Longevity

A healthy young body manufactures all the SAM-e it needs. However, with age, people are less able to produce adequate SAM-e. This may contribute to declining health on many levels. Fortunately, these disturbances are often boosted by SAM-e supplementation.*

In addition, methylation of DNA is an important part of DNA repair. De-methylation of DNA contributes to the aging process. Proper methylation, via substances such as SAM-e, positively influences longevity.*

Healthy Connective Tissue

Research has shown that regular SAM-e supplementation helps support joint health, and is used regularly in Europe to promote joint mobility and comfort.*

Not All SAM-e is Created Equal

SAM-e exists in two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the

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